国立大学法人東海国立大学機構 岐阜大学 応用生物科学部

食品微生物学研究室

研究業績

2024

原著論文・総説

Nakagawa T, Yoshimura A, Sawai Y, Hisamatsu K, Akao T, and Masaki K. 2024. Japanese sake making using wild yeasts isolated from natural environments. 88: 231-236.

Hori M, Kawai Y, Noguchi K, Nakamura K, Shimada M, Iwahashi H, Nagakawa T. 2024. Antimicrobial activity and productivity of γ-aminobutyric acid in lactic acid bacteria isolated from traditional Gifu ayu-narezushi. Food Sci Technol Res. 30: 247-252.

成瀬美卯, 久松賢太郎, 澤井美伯, 吉村明浩, 平塚悟, 島田昌也, 中川智行. 2024. 岐阜大酵母GY115株によるエールビール醸造. 美味技術学会誌. 23: 4-10.

堀光代, 西岡浩貴, 高橋貴洋, 中川智行, 岩橋均. 2024. 長良川鮎なれずしと他産地なれずし5種との比較. 美味技術学会誌. 23: 11-18.

著書・その他

【特集】 酒学 岐大酵母を使用したクラフトビールができるまで. 岐大のいぶき. 46: 4-7.

2023

原著論文・総説

Zhu J, Hikida Y, Cai H-L, Shimada M, Kikukawa H, Nakagawa T. 2023. Growth condition for over production of odd-chain fatty acids in the methylotrophic yeast Komagataella phaffii GS115. Biocatal Agric Biotechnol. 54:102942.

Nakamura K, Mizuno K, Shimada M, Hayakawa T, Nakagawa T. 2023. Genome sequence of the lanthanide-responsive methylotrophic bacterium, Methylorubrum extorquens strain GM97. Microbiol Resour Announc. 12:e0026823.

Ito K, Niwa R, Yamagishi Y, Kobayashi K, Tsuchida Y, Hoshino G, Nakagawa T, Watanabe T. 2023. A unique case in which Kimoto-style fermentation was completed with Leuconostoc as the dominant genus without transitioning to Lactobacillus. J Biosci Bioeng. 135:451-457.

Ito K, Niwa R, Nakagawa T, Hoshino G, and Tsuchida Y. 2023. A dark matter in sake brewing: Origin of microbes producing a Kimoto-style fermentation starter. Front Microbiol. 14:1112638.

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Shimada M, Shirouchi B, Kobayashi Y, Higuchi M, Okumura M, Nakagawa T, Hayakawa T. 2023. Treatment with interleukin-25 suppresses short-term high-fructose diet-induced hepatic gne expression and activities of fatty acid synthesis enzymes in rats. J Oleo Sci, 72:99-104.

2022

原著論文・総説

Hori M, Kawai Y, Nakamura K, Shimada M, Iwahashi H, Nakagawa T. 2022. Characterization of the bacterial community structure in traditional Gifu ayu-narezushi (fermented sweetfish). J Biosci Bioeng, 134:331-337.

Cai HL, Shimada M, Nakagawa T. 2022. The potential and capability of the methylotrophic yeast Ogataea methanolica in a "methanol bio-economy. Yeast, 39:440-448.

Nakamura K, Pastawan V, Suganuma S, Mizuno K, Shimada M, Hayakawa T, Fitriyanto NA, Nakagawa T. 2022. Draft Genome Sequence of Lanthanide-Responsive Bacterium, Bradyrhizobium sp. Strain Ce-3. Microbiol Resour Announc. e0018022.

奥村真衣, 吉村明浩, 澤井美伯, 久松賢太郎, 正木和夫, 島田昌也, 早川享志, 中川智行. 2022. 岐阜大酵母GY115-a3株と岐阜県G酵母NFG株を用いた混合発酵による清酒醸造. 美味技術学会誌. 21:27-31.

奥村真衣, 正木和夫, 吉村明浩, 澤井美伯, 久松賢太郎, 原田雄斗, 岩本悟志, 島田昌也, 早川享志, 中川智行. 2022. 岐阜大泡なし酵母GY115-a3株の交配育種による高発酵・高吟醸香生産型接合変異株の単離とその醸造特性. 日本食品保蔵科学会誌. 48:67-72.

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Hattori Y, Tsutsui S, Yamada C, Kobayashi Y, Nakagawa T, Shimada M. 2022. Dietary supplementation with sodium butyrate reduces high-sucrose diet-induced hepatic accumulation of triacylglycerols and expression of fatty acid synthesis enzymes in rats. J Oleo Sci. 71:1189-1193.

著書・その他

中川智行. 酵母-人類のために進化し続けてきた微生物. 「世界の発酵食をフィールドワークする」 横山智編. 農文協.

2021

原著論文・総説

Doi R, Wu Y, Kawai Y, Wang L, Zendo T, Nakamura K, Suzuki T, Shimada M, Hayakawa T, and Nakagawa T. 2021. Transition and regulation mechanism of bacterial biota in Kishu saba-narezushi (mackerel narezushi) during its fermentation step. J. Biosci. Bioeng. 132: 606-612..

Ma P, Takashima S, Fujita C, Yamada S, Oshima Y, Cai HL, Yurimoto H, Sakai Y, Hayakawa T, Shimada M, Ning X, Wei B, Nakagawa T. 2021. Fatty acid composition of the methylotrophic yeast Komagataella phaffii grown under low- and high-methanol conditions. Yeast. 38: 541-548.

Cai HL, Doi R, Shimada M, Hayakawa T, Nakagawa T. 2021. Metabolic regulation adapting to high methanol environment in the methylotrophic yeast Ogataea methanolica. Microbial Biotechnol. 14: 1512-1524.

Tani A, Mitsui R, Nakagawa T. 2021. Discovery of lanthanide-dependent methylotrophy and screening methods for lanthanide-dependent methylotrophs. Methods Enzymol., 650: 1-18.

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Tanaka T, Mizuno T, Nakagawa T, Hayakawa T, Shimada M. Effects of H3 and H4 histones acetylation and bindings of CREB binding protein and p300 at the promoter on hepatic expression of ɤ-glutamyltransferase gene in a streptozotocin-induced moderate hypoinsulinemic rat model. Physiol Res. 70:475-480.

Hibi M, Sugiura S, Nakagawa T, Hayakawa T, Shimada M. 2021. Effects of dietary supplementation with myo-inositol on hepatic expression of glycolytic and fructolytic enzyme genes in rats fed a high-sucrose diet. J Oleo Sci. 697-702.

Hibi M, Nakagawa T, Hayakawa T, Yanase E, Shimada M. 2021. Dietary supplementation with myo-inositol reduces high-fructose diet-induced hepatic ChREBP binding and acetylation of histones H3 and H4 on the Elovl6 gene in rats. Nutr. Res. 88:28-33.

Shimada M, Hibi M, Nakagawa T, Hayakawa T, Field C.J. 2021. High-fructose diet-induced hepatic expression of the Scd1 gene is associated with increased acetylation of histones H3 and H4 and the binding of ChREBP at the Scd1 promoter in rats. Biomed Res. 42: 85-88.

2020

原著論文・総説・その他

Pastawan V, Fitriyanto NA, Nakagawa T. 2020. Biological function of lanthanide in plant-symbiotic bacteria: Lanthanide-dependent methanol oxidation system. Rev. Agric. Sci., 8: 186-198.

Putri AZ, Nakagawa T. 2020. Microbial α-amylases in the industrial extremozymes. Rev. Agric. Sci. 8:158-169.

Putri AZ, Niwa Y, Ogisu K, Kawasaki S, Shimada M, Hayakawa T, Nakagawa T. 2020. Screening and characterization of amylolytic basidiomycetes yeasts. Food preserv. Sci. 46: 227-235.

Pastawan V, Suganuma S, Mizuno K, Wang L, Tani A, Mistui R, Nakamura K, Shimada M, Hayakawa T, Fitriyanto NA, Nakagawa T. 2020. Regulation of lanthanide-dependent methanol oxidation pathway in the legume symbiotic nitrogen-fixing bacterium Bradyrhizobium sp. strain Ce-3. J. Biosci. Bioeng. 130: 582-587.

Yanpirat P, Nakatsuji Y, Hiraga S, Fujitani Y, Izumi T, Masuda S, Mitsui R, Nakagawa T, Tani A. 2020. Lanthanide-dependent methanol and formaldehyde oxidation in Methylobacterium aquaticum strain 22A. Microorganisms, 8: 822.

Wang L, Hibino A, Suganuma S, Ebihara A, Iwamoto S, Mitsui R⁠, Tani A, Shimada M, Hayakawa T, Nakagawa T. 2020. Preference for particular lanthanide species and thermal stability of XoxFs in Methyorubrum extorquens strain AM1. Enzyme Microb. Technol., 136: 109518.

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Suehiro D, Kawase H, Uehara S, Kawase R, Fukami K, Nakagawa T, Shimada M, Hayakawa T. 2020. Maltobionic acid accelerates recovery from iron deficiency-induced anemia in rats. Biosci. Biotechnol. Biochem. 84: 393-401.

2019

原著論文・総説

Wang L, Suganuma S, Hibino A, Mitsui R, Tani A, Matsumoto T, Ebihara A, Fitriyanto NA, Pertwiningrum A, Shimada M, Hayakawa T, Nakagawa T. 2019. Lanthanide-dependent methanol dehydrogenase from the legume symbiotic nitrogen-fixing bacterium Bradyrhizobium diazoefficiens strain USDA110. Enzyme Microb. Technol. 130: 109371.

Fukuoka H, Kawase T, Oku M, Yurimoto H, Sakai Y, Hayakawa T, Nakagawa T. 2019. Peroxisomal Fba2p and Tal2p complementally function in the rearrangement pathway for xylulose 5-phosphate in the methylotrophic yeast Pichia pastoris. J. Biosci. Bioeng. 128: 33-38.

奥村 真衣,平井 菜未,吉村 明浩,澤井美伯,正木和夫,島田昌也,早川享志,中川智行. 2019. 泡なし岐阜大酵母の育種とその低温醸造条件の検討. 美味技術学会誌. 18(2): 53-57.

奥浜真之助,山中和季,宮崎千保,中本紬,中川智行,楠部真崇. 2019. 名所「道成寺」からの清酒酵母の単離と小仕込み醸造分析. 美味技術学会誌. 18(2): 58-61.

中川 智行, 内田 みなみ, 平井 菜未, 奥村 真衣, 吉村 明浩, 澤井 美伯, 正木 和夫, 二神 泰基, 玉置 尚徳, 向田 潤, 三井 亮司, 稲垣 瑞穂, 島田 昌也, 鈴木 徹, 杉山 誠, 早川 享志. 2019. 新奇清酒酵母の開発に向けた岐阜県自然環境からの出芽酵母のスクリーニングとその清酒醸造特性. 日本醸造協会誌 114(1): 43-52.

中川 智行. 2019. 乳酸菌が醸す発酵食品の世界ー製造過程における乳酸菌の役割と機構ー. New Food Industry. 61(6): 453-459.

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Ichigo Y, Takeshita A, Hibino M, Nakagawa T, Hayakawa T, Patel D, Field C.J., Shimada M. 2019. High-Fructose Diet-Induced Hypertriglyceridemia Is Associated With Enhanced Hepatic Expression of ACAT2 in Rats. Physiol. Res. 68: 1021-1026.

Suehiro D, Okada M, Fukami K, Nakagawa T, Hayakawa T. 2019. Maltobionic acid enhances intestinal absorption of calcium and magnesium in rats. Biosci. Biotechnol. Biochem. 83: 1-8.

Shimada M, Ichigo Y, Shirouchi B, Takashima S, Inagaki M, Nakagawa T, Hayakawa T. 2019. Treatment with myo-inositol attenuates binding of the carbohydrate-responsive element-binding protein to the ChREBP-β and FASN genes in rat nonalcoholic fatty liver induced by high-fructose diet. Nutr. Res. 64: 49-55.

Kitagawa E, Ota Y, Hasegawa M, Nakagawa T, Hayakawa T. 2019. Accumulation of Liver Lipids Induced by Vitamin B6 Deficiency Was Effectively Ameliorated by Choline and, to a Lesser Extent, Betaine. J Nutr Sci Vitaminol (Tokyo). 2019;65: 94-101.

著書・その他

奥村真衣. 若き挑戦者たち. 岐大のいぶき. 38: 6-9.

岐阜大酒「多望の春 岐山/曲阜」完成. 岐大のいぶき. 創立70周年 記念特別号: 30.

2018

原著論文・総説・その他

Masuda S, Suzuki Y, Fujitani Y, Mitsui R, Nakagawa T, Shaintani M, Tani A. 2018. Lanthanide-Dependent Regulation of Methylotrophy in Methylobacterium aquaticum Strain 22A. mSphere. 3(1)

勝野 那嘉子, 吉岡 優, 小栗 唯人, 島田 昌也, 早川 享志, 鈴木 徹, 西津 貴久, 矢部 富雄, 長野 宏子, 中川 智行. 2018. 岐阜県産米ハツシモ,黒糯米,GABA強化米を用いた甘酒アイスの開発とその機能性評価. 美味技術学会誌. 17(2) 55-59.