研究業績

原著論文

2024

• Nagata, N., Ikenaka, Y., Sawamura, H., Sasaki, N. and Takiguchi, M.: Reference intervals for urinary metanephrines to creatinine ratios in dogs in Japan. J. Vet. Med. Sci. 86: 1096-1099, 2024.

• Kida, I., Hayashi, N., Yokoyama, N., Nagata, N., Sasaoka, K., Sasaki, N., Morishita, K., Nakamura, K., Kouguchi, H., Yagi, K., Nakao, R., Takiguchi, M. and Nonaka, N.: Case report: Echinococcus multilocularis infection in a dog showing gastrointestinal signs in Hokkaido, Japan. Front. Vet. Sci. 11: 1373035, 2024.

• Nagata, N., Sawamura, H., Ikenaka, Y., Morishita, K., Hosoya, K., Sasaki, N., Nakamura, K. and Takiguchi, M. Urinary steroid profiling using liquid chromatography-tandem mass spectrometry for the diagnosis of canine Cushing's syndrome. Vet. J. 306: 106151, 2024.

2023

• Ikai, M., Murakami, M., Kanei, T., Asahina, R., Iwata, M., Kamishina, H. and Maeda, S.: Phosphorylation of Janus kinase 1 and signal transducer and activator of transcription 3 and 6 in keratinocytes of canine atopic dermatitis. Vet. Dermatol. 34: 318-326, 2023.
  
  
• Kikukawa, H., Nagao, T., Ota, M., Takashima, S., Kitaguchi, K., Yanase, E., Maeda, S. and Hara, K. Y.: Production of a selective antibacterial fatty acid against Staphylococcus aureus by Bifidobacterium strains. Microbiome Res. Rep. 2: 4, 2023.
  
  
• Yuki, M., Taira, H., Narita, M., Inden, T., Yokota, S., Naito, E. and Maeda, S.: Complete remission of two canine cases with precursor-targeted immune-mediated anemia after combination therapy with prednisolone, cyclosporine, and oclacitinib. Open Vet. J. 13: 1205-1211, 2023.
  
  
• Yokoyama, N., Kinoshita, R., Ohta, H., Okada, K., Shimbo, G., Sasaoka, K., Nagata, N., Sasaki, N., Morishita, K.,Nakamura, K., Kagawa, Y. and Takiguchi, M.: Successful treatment of sclerosing encapsulating peritonitis in a cat using bioresorbable hyaluronate-carboxymethylcellulose membrane after surgical adhesiolysis and long-term prednisolone. JFMS Open Rep. 9: 20551169231209917, 2023.
  
  
• Tamura, J., Yoshida, S., Nagata, N., Shimbo, G. and Oyama, N.: Successful treatment of acute respiratory failure following hypertensive crisis in a dog with presumed pheochromocytoma or paraganglioma. Open Vet. J. 13: 1465-1470, 2023.
  
  
• Teoh, Y. B., Jiang, J-J., Yamasaki, T., Nagata, N., Sugawara, T., Hasebe, R., Ohta, H., Sasaki, N., Yokoyama, N.,Nakamura, K., Kagawa, Y., Takiguchi, M. and Murakami, M.: An inflammatory bowel disease-associated SNP increases local thyroglobulin expression to develop inflammation in miniature dachshunds. Front. Vet. Sci. 10: 1192888, 2023.
  
  
• Yamasaki, T., Nagata, N., Atsumi, T., Hasebe, R., Tanaka, Y., Ohki, I., Kubota, S., Shinohara, Y., Teoh, Y. B., Yokoyama, N., Sasaki, N., Nakamura, K., Ohta, H., Katsurada, T., Matsuno, Y., Hojyo, S., Hashimoto, S., Takiguchi, M. and Murakami, M.: Zoobiquity experiments show the importance of the local MMP9-plasminogen axis in inflammatory bowel diseases in both dogs and patients. Int. Immunol. 35: 313-326, 2023.
  
  
• Nagata, N., Aoshima, K., Nakamura, K. and Takiguchi, M.: Adrenocortical hypoperfusion detected by contrast-enhanced ultrasound in a dog with trilostane-induced hypoadrenocorticism. J. Small. Anim. Pract. 64: 722-726, 2023.

2022

• Kaho Takahashi, Shintaro Kimura, James K Chambers, Yukiko Nakano, Takeshi Ishikawa, Sadatoshi Maeda, Hiroaki Kamishina.; Case Report: Surgical Treatment of Type IV Spinal Dermoid Sinus in a Shiba Inu. Frontiers in veterinary science. 2022 Mar 23.

• Karin Sakamoto, James K. Chambers, Jumpei Fujimoto, Sadatoshi Maeda, Hiroaki Kamishina.; Surgical management of subependymoma in a cat. Veterinary Record Case Reports. 2022 Jun 23.

• Hiroaki Kamishina, Yukiko Nakano, Kohei Nakata, Shintaro Kimura, Yuta Nozue, Adam G Drury, Sadatoshi Maeda.; Microendoscopic Dorsal Laminectomy for Multi-Level Cervical Intervertebral Disc Protrusions in Dogs. Veterinary sciences. 2022 Jan 5.

• Shintaro Kimura, Hiroaki Kamishina, Yoko Hirata, Kyoji Furuta, Yoshiaki Furukawa, Osamu Yamato, Sadatoshi Maeda, Yuji O. Kamatari.; Novel oxindole compounds inhibit the aggregation of amyloidogenic proteins associated with neurodegenerative diseases. Biochimica et Biophysica Acta. 2022 Feb 22.

• Naito, E., Nakata, K., Sakai, H., Yamato, O., Islam, M.S., Maeda, S. and Kamishina, H.: Diffusion tensor imaging-based quantitative analysis of the spinal cord in Pembroke Welsh Corgis with degenerative myelopathy. J. Vet. Med. Sci. 84: 199-207, 2022.
  
  
• Kanei, T., Iwata, M., Kamishina, H., Mizuno, T. and Maeda, S.: Expression and functional analysis of chemokine receptor 7 in canine lymphoma cell lines. J. Vet. Med. Sci. 84: 25-30, 2022.

2021

• Yukina Kuwahara, Karin Yoshizaki, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda, Katsura Takano, Naoki Fujita, Ryohei Nishimura, Jun-Ichiro Jo, Yasuhiko Tabata, Hideo Akiyoshi; Extracellular Vesicles Derived From Canine Mesenchymal Stromal Cells in Serum Free Culture Medium Have Anti-inflammatory Effect on Microglial Cells. Frontiers in veterinary science.2021 Apr 28.

• Shintaro Kimura, Kohei Nakata, Yukiko Nakano, Yuta Nozue, Naoyuki Konno, Taku Sugawara, Sadatoshi Maeda, Hiroaki Kamishina.; Case Report: Spinal Stabilization Surgery Using a Novel Custom-Made Titanium Fixation System for the Spinal Instability Caused by Vertebral Malformation in a Dog. Frontiers in veterinary science.2021 Nov 10.

• Karin Sakamoto, Yuta Nozue, Mami Murakami, Kohei Nakata, Yukiko Nakano, Shinya Soga, Sadatoshi Maeda, Hiroaki Kamishina.; Minimally invasive spinal surgery in a young cat with vertebral hypertrophy. Journal of Feline Medicine and Surgery Open Reports.2021 Oct 6.

• Eiji Naito, Kohei Nakata, Yukiko Nakano, Yuta Nozue, Shintaro Kimura, Hiroki Sakai, Osamu Yamato, Md Shafiqul Islam, Sadatoshi Maeda, Hiroaki Kamishina.; Changes of Dorsal Root Ganglion Volume in Dogs with Clinical Signs of Degenerative Myelopathy Detected by Water-Excitation Magnetic Resonance Imaging. Animals : an open access journal from MDP.2021 Jun 7.

• N Tanaka, S Kimura, Y O Kamatari, K Nakata, Y Kobatake, M Inden, O Yamato, M Urushitani, S Maeda, H Kamishina. In vitro evidence of propagation of superoxide dismutase-1 protein aggregation in canine degenerative myelopathy. Veterinary journal.2021 Jun 21.

• Nana Tanaka, Toshitaka Kanei, Munetaka Iwata, Mifumi Kawabe, Hiroaki Kamishina, Mami Murakami, Hiroki Sakai, Sadatoshi Maeda.; Detection of granzyme B in CD3-positive cells infiltrated in lesional skin of a dog with erythema multiforme associated with zonisamide. The Journal of veterinary medical science.2021 Aug 25.

• Yui Kobatake, Kohei Nakata, Hiroki Sakai, Jun Sasaki, Osamu Yamato, Satoshi Takashima, Naohito Nishii, Sadatoshi Maeda, Md Shafiqul Islam, Hiroaki Kamishina.; The Long-Term Clinical Course of Canine Degenerative Myelopathy and Therapeutic Potential of Curcumin. Veterinary sciences.2021 Sep 12.

• Hiroaki Kamishina, Yukiko Nakano, Yuta Nozue, Kohei Nakata, Shintaro Kimura, Adam G Drury, Sadatoshi Maeda.; Microendoscopic Mini-Hemilaminectomy and Discectomy in Acute Thoracolumbar Disc Extrusion Dogs: A Pilot Study. Veterinary sciences.2021 Oct 18.

• Toshitaka Kanei, Munetaka Iwata, Hiroaki Kamishina, Takuya Mizuno, Sadatoshi Maeda.; Expression and functional analysis of chemokine receptor 7 in canine lymphoma cell lines. The Journal of veterinary medical science. 2021 Dec 3.

• Eiji Naito, Kohei Nakata, Hiroki Sakai, Osamu Yamato, Md Shafiqul Islam, Sadatoshi Maeda, Hiroaki Kamishina.; Diffusion tensor imaging-based quantitative analysis of the spinal cord in Pembroke Welsh Corgis with degenerative myelopathy. The Journal of veterinary medical science. 2021 Dec 13.

2020

• Toru Fujioka, Kohei Nakata, Yukiko Nakano, Yuta Nozue, Taku Sugawara, Naoyuki Konno, Sadatoshi Maeda, Hiroaki Kamishina.; Accuracy and Efficacy of a Patient-Specific Drill Guide Template System for Lumbosacral Junction Fixation in Medium and Small Dogs: Cadaveric Study and Clinical Cases. Frontiers in veterinary science.2020 Jan 9.

• Momoko Narita, Hidetaka Nishida, Sho Goto, Mami Murakami, Hiroki Sakai, Kohei Nakata, Sadatoshi Maeda, Hiroaki Kamishina.; Primary malignant peripheral nerve sheath tumors arising from the spinal canal invading the abdominal cavity in a dog. Journal of Veterinary Medical Science.2020 Apr 9.

• Shintaro Kimura, Yuji O Kamatari, Yukina Kuwahara, Hideaki Hara, Osamu Yamato, Sadatoshi Maeda, Hiroaki Kamishina, Ryo Honda.; Canine SOD1 harboring E40K or T18S mutations promotes protein aggregation without reducing the global structural stability. PeerJ.2020 Jul 15.

• Momoko Narita, Hidetaka Nishida, Ryota Asahina, Kohei Nakata, Hirohito Yano, Peter J Dickinson, Toshiyuki Tanaka, Hideo Akiyoshi, Sadatoshi Maeda, Hiroaki Kamishina.; Expression of microRNAs in plasma and in extracellular vesicles derived from plasma for dogs with glioma and dogs with other brain diseases. American journal of veterinary research. 2020 Apr.

• Shintaro Kimura, Kohei Nakata, Asuka Sube, Takashi Kuniya, Naoyuki Watanabe, Kayoko Yonemaru, Sadatoshi Maeda, Hiroaki Kamishina.; Encapsulated gas accumulation in the spinal canal: pneumorrhachis in two dogs. The Journal of veterinary medical science.2020 Aug 7.

• Ryota Asahina, Kazunori Ueda, Yuri Oshima, Toshitaka Kanei, Masahiro Kato, Masutaka Furue, Toshihiro Tsukui, Masahiko Nagata, Sadatoshi Maeda.; Serum canine thymus and activation-regulated chemokine (TARC/CCL17) concentrations correlate with disease severity and therapeutic responses in dogs with atopic dermatitis. Veterinary dermatology.2020 Sep 17.

• Kei Hashimoto, Yui Kobatake, Ryota Asahina, Osamu Yamato, Md Shafiqul Islam, Hiroki Sakai, Hidetaka Nishida, Sadatoshi Maeda, Hiroaki Kamishina.; Up-regulated inflammatory signatures of the spinal cord in canine degenerative myelopathy. Research in veterinary science.2020 Nov 5.

• Kohei Nakata, Mariko Namiki, Yui Kobatake, Hidetaka Nishida, Hiroki Sakai, Osamu Yamato, Makoto Urushitani, Sadatoshi Maeda, Hiroaki Kamishina.; Up-regulated spinal microRNAs induce aggregation of superoxide dismutase 1 protein in canine degenerative myelopathy. Research in veterinary science.2020 Nov 25.

2019

• Satoshi Akiyama, Ryota Asahina, Hiroshi Ohta, Toshihiro Tsukui, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda.; Th17 cells increase during maturation in peripheral blood of healthy dogs. Veterinary immunology and immunopathology.2019 Feb 5.

• Momoko Narita, Hidetaka Nishida, Ryota Asahina, Kohei Nakata, Hirohito Yano, Tomoyuki Ueda, Masatoshi Inden, Hideo Akiyoshi, Sadatoshi Maeda, Hiroaki Kamishina.; Identification of reference genes for microRNAs of extracellular vesicles isolated from plasma samples of healthy dogs by ultracentrifugation, precipitation, and membrane affinity chromatography methods. American journal of veterinary research. 2019 Mar 1.

• Hidetaka Nishida, Midori Yamazaki, Hiroki Sakai, Sadatoshi Maeda, Hiroaki Kamishina.; Intracranial ectopic choroid plexus cyst in a dog. Journal of Veterinary Medical Science.2019 Mar 14.

• Nishida H, Nakata K, Maeda S, Kamishina H.;Prevalence and pattern of thoracolumbar caudal articular process anomalies and intervertebral disk herniations in pugs. The Journal of veterinary medical science.2019 May 21.

• Kamishina H, Sugawara T, Nakata K, Nishida H, Yada N, Fujioka T, Nagata Y, Doi A, Konno N, Uchida F, Maeda S.; Clinical application of 3D printing technology to the surgical treatment of atlantoaxial subluxation in small breed dogs. PloS one. 2019 May 3.

• 前田 貞俊.; 犬アトピー性皮膚炎の診断および治療に関する指針作成の試み 現状と課題 . 獣医臨床皮膚科.2019 Jun.

• Kohei Nakata, Kazuki Heishima, Hiroki Sakai, Osamu Yamato, Yu Furusawa, Hidetaka Nishida, Sadatoshi Maeda, Hiroaki Kamishina.; Plasma microRNA miR-26b as a potential diagnostic biomarker of degenerative myelopathy in Pembroke welsh corgis . BMC Veterinary Research.2019 Jun 10.

• 山内麻莉, 西田英高, 西田英高, 柳井徳磨, 前田貞俊, 神志那弘明.; 脊髄円錐の障害によって尾の遠位の痛覚消失を伴った猫の腰椎椎間板ヘルニアの1例 . 日本獣医師会雑誌. 2019年2月20日

2018

• Ikeuchi M, Asahina R, Nishida H, Kamishina H, Kitoh K, Sakai H, Maeda S.;Phenotypic analysis of mice xenografted with canine epitheliotropic cutaneous T-cell lymphoma cells.Vet Dermatol. 2018 Aug 30.
• Teramoto K, Asahina R, Nishida H, Kamishina H, Maeda S.;Expression of ZO-1 and claudin-1 in a 3D epidermal equivalent using canine progenitor epidermal keratinocytes.Vet Dermatol. 2018 May 21
• Asahina R, Nishida H, Kamishina H, Maeda S.;Expression of IL-33 in chronic lesional skin of canine atopic dermatitis.Vet Dermatol. 2018 Jun;29
• Asahina R, Nishida H, Kamishina H, Maeda S.;Transcriptional analysis of the IL-33 receptor suppression of tumourigenicity 2 and its effects on canine Type 2 T helper cells: a preliminary study.Vet Dermatol. 2018 Apr;29

2017

• Hara K, Iio A, Asahina R, Takahashi M, Mori T, Nishida H, Kamishina H, Sakai H, Kitoh K, Mizuno T, Tsujimoto H, Maeda S;Characterization of a novel canine T-cell line established from a dog with cutaneous T-cell lymphoma.J Dermatol Sci. 2017 Nov;88
• Kobatake Y, Sakai H, Tsukui T, Yamato O, Kohyama M, Sasaki J, Kato S, Urushitani M, Maeda S, Kamishina H.;Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy.J Neurol Sci. 2017 Jan 15
• Asahina R, Maeda S.;A review of the roles of keratinocyte-derived cytokines and chemokines in the pathogenesis of atopic dermatitis in humans and dogs.Vet Dermatol. 2017 Feb;28

2016

• Sakamoto M, Asahina R, Kamishina H, Maeda S.;Transcription of thymic stromal lymphopoietin via Toll-like receptor 2 in canine keratinocytes: a possible association of Staphylococcus spp. in the deterioration of allergic inflammation in canine atopic dermatitis.Vet Dermatol. 2016 Jun;27

2015

• Asahina R, Kamishina H, Kamishina H, Maeda S.;Gene transcription of pro-inflammatory cytokines and chemokines induced by IL-17A in canine keratinocytes.Vet Dermatol. 2015 Dec 26
• S. Nakamae, Y. Kobatake, R. Suzuki, T. Tsukui, S. Kato, O. Yamato, H. Sakai, M. Urushitani, S. Maeda, H. Kamishina, ; Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy. Neuroscience. 2015 Jul 8; 303: 229-240.
• E. Naito, D. Kudo, SI. Sekine, K. Watanabe, Y. Kobatake, N. Tamaoki, M. Inden, K. Iida, Y. Ito, I. Hozumi, T. Shibata, S. Maeda, H. Kamishina, ;Characterization of canine dental pulp cell and their neuroregenerative potential. In Vitro Cell Dev Biol Anim. 2015 Jul 14.

2014

• A. Iio, T. Motohashi, T. Kunisada, Y. Yasuhira, H. Kamishina, S. Maeda, ; Preferential gene transcription of T helper 2 cytokines in peripheral CCR4 CD4 lymphocytes in dogs. Vet Dermatol. 25: 199-e150, 2014.

2013

• T. Kimura, M. Sekido, A. Iio, N. Chimura, S. Shibata, H. Kamishina and S. Maeda,: Involvement of nuclear factor of activated T cells in granulocyte-macrophage colony-stimulating factor production in canine keratinocytes stimulated with a cysteine protease. Vet Dermatol. 24(3): 310-314, e369, 2013.
• Y. Kobatake, T. Miyabayashi, N. Yada, S. Kachi, G. Ohta, H. Sakai, S. Maeda and H. Kamishina,: Magnetic Resonance Imaging Diagnosis of Dandy-Walker-Like Syndrome in a Wire-Haired Miniature Dachshund. J Vet Med Sci. 75(10): 1379-1381, 2013.
• N. Chimura, A. Iio, E. Ozaki, T. Mori, Y. Ito, N. Murayama, M. Nagata, K. Ide, K. Nishifuji, H. Kamishina, S. Maeda : Transcription profile of chemokine receptors, cytokines and cytotoxic markers in peripheral blood of dogs with epitheliotropic cutaneous lymphoma. Vet Dermatol. 24: 628-631, e155, 2013.

2012

• T. Kimura, M. Sekido, N. Chimura, S. Shibata, N. Kondo, H. Kamishina and S. Maeda,: Production of GM-CSF mediated by cysteine protease of Der f in canine keratinocytes. J Vet Med Sci. 74(8): 1033-1036, 2012.

2011

• N. Chimura, N. Kondo, S. Shibata, T. Kimura, T. Mori, Y. Hoshino, N. Murayama, M. Nagata, K. Ide, K. Nishifuji, H. Kamishina and S. Maeda,: Gene transcription analysis in lesional skin of canine epitheliotropic cutaneous lymphoma using quantitative real-time RT-PCR. Vet Immunol Immunopathol. 144(3-4): 329-336, 2011.
• N. Chimura, S. Shibata, T. Kimura, N. Kondo, T. Mori, Y. Hoshino, H. Kamishina and S. Maeda,: Suitable reference genes for quantitative real-time rt-pcr in total RNA extracted from canine whole blood using the PAXgene™ system. J Vet Med Sci. 73(8): 1101-1104, 2011.
• S. Shibata, S. Maeda, N. Kondo, A. Inoue, N. Chimura and T. Fukata,: Effect of recombinant canine interferon-γ on granulocyte-macrophage colony-stimulating factor, transforming growth factor-β and CC chemokine ligand 17 mRNA transcription in a canine keratinocyte cell line (CPEK). Vet Dermatol. 22(1): 24-30, 2011.
• S. Shibata, S. Maeda, N. Kondo, N. Chimura, A. Inoue and T. Fukata,: Identification of the signaling pathway of TNF-α-induced CCL17/TARC transcription in a canine keratinocyte cell line. Vet Immunol Immunopathol. 139(2-4): 90-98, 2011.

学位論文

2013

2012

卒業論文

2013

2012

2011