研究業績 research achievements

原著論文　2024年

Elsaman, T., Muddathir, A. M., Mohieldin, E. A. M., Batubara, I., Rahminiwati, M., Yamauchi K., Mohamed, M. A., Asoka, S. F., Büsselberg, D., Habtemariam, S., Sharif‑Rad, J.:Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure-activity relationship, and prospects for clinical advancement. Pharmacological Reports, in press.

Tsuchiya, A., Suzuki, M., Ito, R., Batubara, I., Yamauchi, K., Mitsunaga, T. New flavan trimer from Daemonorops draco as osteoclastogenesis inhibitor. Fitoteraia, 2024, 172, 105757.

Badrunanto, Wahyuni, W.T., Farid, M., Batubara, I., Yamauchi, K. Antioxidant components of the three different varieties of Indonesian ginger essential oil: In vitro and computational studies. Food Chemistry Advances, 2024, 4, 100558.

学会発表　2024年

○Yen Thi Hoang Kieu, Kosei Yamauchi, Tohru Mitsunaga「Molecular networking assisted in the rapid discovery of bioactive compounds from Excoecaria cochinchinensis leaves」第74回日本木材学会　2024年3月

○Saat Egra, Kosei Yamauchi, Tohru Mitsunaga, Harlinda Kuspradini, Irawan Wijaya Kusuma, Irmanida Batubara「Garcidepsidon B from Garcinia parvifolia: Antimicrobial Activities of The Medicinal Plants from North Kalimantan against Dental Caries and Periodontal Disease Pathogens」第74回日本木材学会　2024年3月

○土屋 綾香、中嶋 和紀、山内 恒生、光永 徹「 Daemonorops draco果実由来竜血成分の骨粗鬆症抑制効果と作用機序の一考察」第74回日本木材学会　2024年3月

○竹山 大暁、山内 恒生、光永 徹「マウスのストレス性脳障害改善に及ぼすスギ材精油香気成分Ⅲ」第74回日本木材学会　2024年3月

受賞

第十回日本木材学会優秀女子学生賞　土屋綾香「癌細胞の遊走と破骨細胞形成阻害を示すインドネシア産薬用植物由来フラボノイド」

学生優秀口頭発表賞　竹山 大暁「マウスのストレス性脳障害改善に及ぼすスギ材精油香気成分Ⅲ 」

招待講演

Kosei Yamauchi Utilization of bioactive compound from plants. International Conference on Climate Change, Agriculture, Biodiversity, and Environment Study. 2024, January, online. (Keynote Speaker)

原著論文 2023年

原著論文 2022年

Rafi, M., Kasutsar, A., Septaningsih, D.A., Melati, P., Heryanto, R., Batubara, I., Mitsunaga, T., Susanti, E. Feasibility of near-infrared spectroscopy and chemometrics analysis for discrimination of Cymbopogon nardus from Cymbopogon citratus. Arabian Journal of Chemistry, 2022, 15(12), 104277.

Sakamoto, K., Watanabe, C., Masutani, T., Hirasawa, A.,Wakamatsu, K., Iddamalgoda, A., Kakumu, Y., Yamauchi, K., Mitsunaga, T., Arnica montana L. extract containing 6-O-methacryloylhelenalin and 6-O-isobutyrylhelenalin accelerates growth and differentiation of human subcutaneous preadipocytes and leads volumizing of skin. International journal of cosmetic science, 2022, 45(1), 1-13.

Kakumu, Y., Thi Nguyen, M.T., Mitsunaga, T. Molecular networking-based discovery of anti-inflammatiory chromene dimers from Melicope pteleifolia. Phytochemistry, 2022, 202, 113322.

Tsuchiya, A., Kobayashi, M., Kamatari, Y.O., Mitsunaga, T., Yamauchi, K. Development of flavonoid probes and the binding mode of the target protein and quercetin derivatives. Bioorganic and Medicinal Chenistry, 2022, 68, 116854.

Hattori, H., Moriyama, A., Ohno, T., Shibata, T., Iwahashi, H., Mitsunaga, T. Molecular networking-based lipid profiling and multi-omics approaches reveal new contributions of functional vanilloids to gut microbiota and lipometabolism changes. Food Chemistry: Molecular Sciences, 2022, 5, 100123.

Kartina, Batubara, I., Kuspradini, H., Kusuma, I.W., Wahyuni, W.T., Egra, S., Mitsunaga, T. Diversity of medicinal plants used for skincare by Bulungan tribe in North Kalimantan, Indonesia and its melanin biosynthesis inhibition. Blodlversltas, 2022, 23(3), 1246-1253.

Nguyen, V.-K., Nguyen-Si, H.-V., Devi, A.P., Poonsukkho, P., Sangvichien, EK., Tran T-N., Hioki, Y., Mitsunaga, T., Chavasiri, W.:Eumitrins F-H: three new xanthone dimers from the lichen Usnea baileyi and their biological activities.Natural Product Research, 2022, 5(1), 1-11.

Kakumu, Y., Nguyen, T.M.T., Yamauchi, K., Mitsunaga, T.:New benzoic acid and caffeoyl derivatives with anti-inflammatory activities isolated from leaves of Ilex kaushue.Natural Product Research, 2022, 36(12), 3013-3021.

学会発表 2022年

○多賀 勇亮、光永 徹、山内 恒生　「パープルハート (Peltogyne spp.) 心材色素成分の構造に関する研究」第72回日本木材学会大会　2022　3月

○各務 裕也、光永 徹、Nguyen Thi Minh Tu「分子ネットワークを用いたベトナム産薬用植物由来新規抗炎症クロメ ン二量体の発見と構造決定」第72回日本木材学会大会　2022　3月

○征矢野 真由、山内 恒生、光永 徹　「紫夏藤由来縮合型タンニンの構造解析および GTase阻害活性」第72回日本木材学会大会　2022　3月

○土屋 綾香、山内 恒生、光永　徹「破骨細胞分化抑制活性を有するDaemonorops draco 由来竜血に含ま れる抽出成分の単離同定」第72回日本木材学会大会　2022　3月

〇鈴木真希、各務裕也、山内恒生、光永　徹、Mihn Tu Thi Nguyen「苦丁茶は成分の破骨細胞分化に及ぼす効果」日本生薬学会　第68回年会、2022年9月

〇多賀勇亮、光永徹、山内恒生「有色木材心材の色調変化メカニズムの解明」日本ポリフェノール学会第15回学術集会、2022年8月

〇山内恒生、征矢野真由、小林美穂、鎌足雄司、光永　徹「縮合型タンニンのタンパク質凝集モデル」日本ポリフェノール学会第15回学術集会、2022年8月

〇土屋綾香、山内恒生、光永　徹「破骨細胞分化抑制活性を有するDaemonorops draco抽出物の成分探索」日本ポリフェノール学会第15回学術集会、2022年8月

〇山内恒生、菅原由喜、征矢野真由、小林美穂、鎌足雄司、光永　徹「NMRを用いたタンニンのタンパク質凝集メカニズムの解明」日本木材学会中部支部大会、2022年10月

〇土屋綾香、イルマニダバツバラ、山内恒生、光永　徹「破骨細胞分化抑制活性を有するDaemonorops draco抽出物の成分探索とそのメカニズム」日本木材学会中部支部大会、2022年10月

受賞 2022年

優秀発表賞　〇山内恒生、征矢野真由、小林美穂、鎌足雄司、光永　徹「縮合型タンニンのタンパク質凝集モデル」日本ポリフェノール学会第15回学術集会、2022年8月

原著論文 2021年

Hattori, H., Mori, T., Shibata, T., Kita, M., Mitsunaga, T.: 6-Paradol Acts as a Potential Anti-obesity Vanilloid from Grains of Paradis. Molecular Nutrition and Food Research, 2021, 65(16), 2100185

Takayama, S., Kawanishi, M., Yamauchi, K., Tokumitsu, D., Kojima, H., Masutani, T., Iddamalgoda, A., Mitsunaga, T., Tanaka, H.:Ellagitannins from Rosa roxburghii suppress poly(I:C)-induced IL-8 production in human keratinocytes.Journal of Natural Medicines, 2021, 75(3), 623-632

学会発表 2021年

○征矢野 真由、山内恒生、光永 徹　紫夏藤 (Millettia reticulata) 由来縮合型タンニンの構造解析とGTase阻害活性 （岐阜大院自然研）2021年度　日本木材学会中部支部大会　2021年 11月

○林　貴之、山内恒生、光永徹　第65回　香料・テルペン及び精油化学に関する討論会　サイプレス材精油雰囲気下におけるマウスの肥満抑制作用とその作用機作　2021年 10月

○山内恒生，土屋綾香，小林美穂，　鎌足雄司,　光永　徹　がん遊走を阻害するquercetin誘導体の標的タンパク質の探索と作用機序の解明　日本ポリフェノール学会第14回学術集会　2021年　9月

○土屋綾香，山内恒生，光永　徹　破骨細胞分化抑制活性を有する, Daemonorops draco抽出物の成分探索　日本ポリフェノール学会第14回学術集会　2021年　9月

○多賀 勇亮，山内 恒生 ，光永 徹　パープルハート(Peltogyne spp.) 芯材色素成分の構造と色調発現に関する研究　日本ポリフェノール学会第14回学術集会　2021年　9月

○Maki Suzuki, Minh Tu Thi Nguyen, Kosei Yamauchi, Tohru Mitsunaga Structural analysis of saponins from the leaves of Ilex kaushue (Kudingcha). The 11th JCK Joint Symposium on Pharmacognosy. 2021

○Runa Fujimoto, Masahiro Kassai, Kosei Yamauchi , Tohru Mitsunaga Neurite outgrowth effect on PC12 cells from Piper longum fruit extracts. The 11th JCK Joint Symposium on Pharmacognosy. 2021

○Yuya Kakumu, Minh Tu Thi Nguyen, Tohru Mitsunaga Molecular Networking-based isolation of dimeric chromenes from leaves of Melicope pteleifolia. The 11th JCK Joint Symposium on Pharmacognosy. 2021

○Takafumi Hara, Masahiro Kassai, Kosei Yamauchi, Tohru Mitsunaga Identification of NK cell activator from Citrus hystrix leaf extracts. The 11th JCK Joint Symposium on Pharmacognosy. 2021

○福岡　晃帆，山内　恒生，光永　徹　ヒノキ科木材精油香気がマウスの記憶・学習障害の改善に与える効果　第71回日本木材学会大会　2021　3月

○豊田 梨帆，山内　恒生，光永　徹　ウェンジ (Millettia laurentii) 心材抽出成分の単離・同定および色素成分の 変退色挙動の解明　第71回日本木材学会大会　2021　3月

○林 貴之，山内　恒生，光永　徹　サイプレス材精油香気雰囲気下飼育によるマウスの肥満抑制 メカニズムの解明　第71回日本木材学会大会　2021　3月

○日置 裕介 ，Siaw ONWONA-AGYEMAN，山内　恒生，光永　徹　Garcinia kola 種子抽出成分の探索と口腔疾患原因菌に対する抗菌活性　第71回日本木材学会大会　2021　3月

招待講演

○Kosei Yamauchi, Ayaka Tsuchiya, Tohru Mitsunaga: Investigation of Bioactivity Mechanism of Flavonoids in Cancer Cells. Annual Meeting of the Korean Society of Wood Science and Technology 2021

○Kosei Yamauchi: Strategy on elucidation of bioactivity mechanism of flavonoids. Kalimantan Plant Biodiversity For The Development Of Medicines Seminar Series 2021 (Keynote speaker)

○Kosei Yamauchi:Bioactivity and mechanism of components in medicinal plant. International Guest Lectures on Role Secondary Metabolite in Medicinal Plants 2021

受賞 2021年

優秀発表賞　征矢野 真由　2021 年度 日本木材学会中部支部大会　　「紫夏藤 (Millettia reticulata) 由来縮合型タンニンの構造解析とGTase阻害活性」

ベストプレゼンテーション賞　林　貴之　第65回　香料・テルペン及び精油化学に関する討論会　「サイプレス材精油雰囲気下におけるマウスの肥満抑制作用とその作用機作」　

若手優秀発表賞　山内恒生　日本ポリフェノール学会第14回学術集会　「がん遊走を阻害するquercetin誘導体の標的タンパク質の探索と作用機序の解明」

原著論文 2020年

Hioki, Y., Onwona-Agyeman, S., Kakumu, Y., Hattori, H., Yamauchi, K., Mitsunaga, T.: Garcinoic Acids and a benzophenone derivative from the seed of Garcinia kola and their antibacterial activities against oral bacterial pathogenic organisms. Journal of Natural Products, 83: 2087-2092, 2020.

Wang, X., Yamauchi, K., Mitsunaga, T.: A review on osteoclast diseases and osteoclastogenesis inhibitors recently developed from natural resources. Fitoterapia, 142: 104482, 2020.

Yamaguchi K., Mitsunaga T., Yamauchi K.: 6-Paradol and its glucoside improve memory disorder in mice. Food and Function, 11(11), 9892-9902, 2020.

Muddathir, A.M., Mohieldin, E.A.M., Mitsunaga, T. In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant BMC Complementary Medicine and Therapies, 20(1), 360, 2020.

学会発表 2020年

Mitsunaga T.: Natural Product Chemmistry -the potential of natural medicine-. Guest General lecture of Sebelas Maret University 2020

Yamauchi K.: Natural Product Chemmistry -the potential of natural medicine-. Guest General lecture of Sebelas Maret University 2020

Mitsunaga T.: Can the natural product constituents from medicinal plants or functional food materials contribute to improvement/prevention of Alzheimer's type dementia? International Symposium on Food Sciences 2020

Kakumu, Y., Nguyen, T.M.T., Yamauchi, K. Mitsunaga T.: Anti-inflammatory phenolics from the leaves of Ilex kaushue. International Symposium on Food Sciences 2020

Yamauchi, K. Tsuchiya, A., Mitsunaga T.: Multiple bioactivities of flavonoids. International Symposium on Food Sciences 2020

○福岡　晃帆，山内　恒生，光永　徹　ヒノキ科樹木材精油香気成分が慢性ストレス負荷マウスに与える影響 第64回香料・テルペンおよび精油化学に関する討論会　2020　10月

○福岡　晃帆，山内　恒生，光永　徹　針葉樹材精油香気成分の吸入によるマウスの記憶・学習障害改善に及ぼす効果 第70回日本木材学会大会　2020　3月

○外島　響，山内　恒生，光永　徹　イロハモミジ（Acer palmatum）葉抽出成分の単離・同定と機能性の探索 第70回日本木材学会大会　2020　3月

○服部　浩之，山内　恒生，光永　徹　香辛料Grains of Paradise成分の肥満抑制効果とその分子メカニズムの網羅的解明 第70回日本木材学会大会　2020　3月

○日置　裕介，Siaw ONWONA-AGYEMAN，山内　恒生，光永　徹　Garcinia kola種子抽出成分の探索と口腔疾患予防に関する研究 第70回日本木材学会大会　2020　3月

○各務　裕也，NGUYEN Thi Minh tu，山内　恒生，光永　徹　ベトナム産苦丁茶の二次代謝成分探索と生理活性 第70回日本木材学会大会　2020　3月

原著論文 2019年

Egra S., Amarullah, Sekarsari R.A., Kuspradini H., Mitsunaga T. Potential of dayak onion (Eleutherine palmifolia l merr) extract as natural pesticide for bacteria causing wilt disease. Inernational Journal of Scientific and Technology Research, 8: 244-248, 2019.

Jiang L., Yanase E., Mori T., Kurata K., Toyama M., Tsuchiya A., Yamauchi K., Mitsunaga T., Iwahashi H., Takahashi J. Relationship between Flavonoid Structure and Reactive Oxygen Species Generation upon Ultraviolet and X-ray Irradiation. Journal of Photochemistry and Photobiology A: Chemistry, 384: 112044, 2019.

Wang X., Batubara I., Yamauchi K., Mitsunaga T. Identification and structure-activity relationship (SAR) of chemical constituents from Daemonorops draco (Willd.) Blume and selected commercial flavonoids on anti-osteoclastogenesis activity. Fitoterapia, 138: 104280, 2019.

Hattori H., Mitsunaga T., Clive L.J.D. Synthesis of Phenolic Components of Grains of Paradise. Tetrahedron Letters 60: 1989-1991, 2019.

Yamauchi K., Natsume M., Yamaguchi K., Batubara I., Mitsunaga T. Structure-activity relationship for vanilloid compounds from extract of Zingiber officinale var rubrum rhizomes: Effect on extracellular melanogenesis inhibitory activity. Medicinal Chemistry Research, 28: 1402-1412, 2019.

Kakumu Y., Yamauchi K., Mitsunaga T. Identification of chemical constituents from the bark of Larix kaempferi and their tyrosinase inhibitory effect. Holzforschung, 73: 637-643, 2019.

Masum　M.N., Choodej S., Yamauchi K., Mitsunaga T., Isolation of phenylpropanoid sucrose esters from the roots of Persicaria orientalis and their potential as inhibitors of melanogenesis. Medicinal Chemistry Research, 28: 623-632, 2019.

Masum M.N.,Yamauchi K., Mitsunaga T., Tyrosinase Inhibitors from Natural and Synthetic Sources as Skin-lightening Agents. Reviews in Agricultural Science, 7: 41-58, 2019.

Choodej S., Pudhom K., Yamauchi K., Mitsunaga T., Inhibition of melanin production by sesquiterpene lactones from Saussurea lappa and their analogues. Medicinal Chemistry Research, 28(6): 857-862.

山内恒生 熱帯産薬用植物成分の生理活性と作用メカニズム Green Spirits, 2019, 14: 1, 2-8

学会発表 2019年

口頭発表

○日置　裕介，山内　恒生，光永　徹　アフリカ伝統生薬 Garcinia kola 種子抽出成分の検索と口腔疾患予防に関する研究　日本生薬学会第66回年会　2019　9月

○山口　佳穂，山内 　恒生，光永 　徹　Grains of Paradise 種子抽出成分の配糖化と神経変性疾患に与える影響　第2回樹木抽出成分討論会　2019　9月

○山口　佳穂，服部　浩之，山内　恒生，光永　徹，（農工大院農）アジマン　スィアウ　Grains of Paradise種子抽出成分の配糖化とスコポラミン誘導性記憶障害に対する効果 第69回日本木材学会大会　2019　3月

○各務　裕也，山内　恒生，光永　徹　カラマツ樹皮抽出成分の構造解析とチロシナーゼ阻害活性 第69回日本木材学会大会　2019　3月

○土屋　綾香，山内　恒生，光永　徹　3-O-methylquercetinのガン転移抑制メカニズムに関する研究 第69回日本木材学会大会　2019　3月

○竹内　瑞紀，山内　恒生，光永　徹，（ボゴール農科大）IRMANIDA Batubara　Murraya paniculata葉抽出物に含まれる化合物の単離・同定とPC12細胞の神経突起伸長作用 第69回日本木材学会大会　2019　3月

○福岡　晃帆，山内　恒生，光永　徹 　能登ヒバ材香気成分がラット交感神経活動に及ぼす効果 第69回日本木材学会大会　2019　3月　

Sugama, C., Yamauchi, K., Mitsunaga, T.: Anti-stress activity of the essential oil flavor from Alpinia zerumbet var. Excelsa. The 2nd International Conference of Essential oil 2019, 2019, (Indonesia).

Fukuoka, A., Yamauchi, K., Mitsunaga, T.: Stress reduction effect of wood essential oil flavours on Chronic Unpredicable Mild Stress (CUMS) mice. The 2nd International Conference of Essential oil 2019, 2019, (Indonesia).

Mitsunaga, T.: Effects of Essential Oil Flavors from Biomass on Autonomic Nerve Activity and Endocrine Hormone in Animals. The 2nd International Conference of Essential oil 2019, 2019, (Indonesia). Keynote Speaker

ポスター発表

○豊田　梨帆，山内　恒生，光永　徹　ウェンジ心材色素成分の単離・同定および変退色メカニズムの解明 第69回日本木材学会大会　2019　3月

○外島　響，山内　恒生，光永　徹，（もみじかえで研究所）本間　篤史　イロハモミジ (Acer palmatum) 葉抽出成分に関する研究 第69回日本木材学会大会　2019　3月

○伊藤　弘騎，山内　恒生，光永　徹　サイプレス材精油香気成分がラット交感神経活動に及ぼす影響 -シトロネル酸の役割について- 第69回日本木材学会大会　2019　3月

○川西　美帆，山内　恒生，光永　徹，（一丸ファルコス）高山　悟，ARUNASIRI Iddamalgoda　 Rosa roxburghii果実抽出物の分画と単離化合物の構造解析 第69回日本木材学会大会　2019　3月

○須蒲　千晶，山内　恒生，光永　徹　沖縄県産タイリン月桃葉精油の香気成分が交感神経活動に及ぼす影響 第69回日本木材学会大会　2019　3月

原著論文 2018年

Yamauchi, K., Fujieda, A., Mitsunaga, T. Selective synthesis of 7-O-substituted luteolin derivatives and their melanonenesis and proliferation inhibitory activity in B16 melanoma cells. Bioorganic & Medicinal Chemistry Letters, 28: 2518-2522, 2018.

Choodej, S., Pudhom, K., Mitsunaga, T. Inhibition of TNF-α-Induced inflammation by sesquiterpene lactones from Saussurea lappa and semi-synthetic analogues. Planta Medica, 84: 329-335, 2018.

Zuberi Ashraf, A.H.M.Afroze, S.H.,Yamauchi, K., Zawieja, D.C., Keuhl, T.J., Erlandson, L.W., Uddin, M.N. Differential mechanism of action of 3,4',7-O-trimethylquercetin in three types of ovarian cancer cells. Anticancer Research, 38: 5131-5137, 2018.

Setyawati, A., Hirabayashi, K., Yamauchi, K., Hattori, H., Mitsunaga, T., Batubara, I., Heryanto, R., Hashimoto, H., Hotta, M. Melanogenesis inhibitory activity of components from Salam leaf (Syzygium polyanthum) extract. Journal of Natural Medicines, 72: 474-480, 2018.

Yamauchi, K., Mitsunaga, T. Methylquercetins stimulate melanin biosynthesis in a three-dimensinal skin model. Journal of Natural Medicines, 72: 563-569, 2018.

Setyawati, A., Yamauchi, K., Mitsunaga, T. Potential of Medicinal Plants Extractives as Anti-Melanogenesis Ingredients. Reviews in Agricultural Science, 6: 46-60, 2018.

Kuspradini, H., Putri, A.S., Mitsunaga,T. Chemical Composition, Antibacterial and Antioxidant Activities of Essential Oils of Dryobalanops lanceolata Burck. Leaf. Research Journal of Medicinal Plants, 12: 19-25, 2018.

Hattori, H., Yamauchi, K., Onwona-Agyeman,S., Mitsunaga. T. Identification of vanilloid compounds in the Grains of Paradise and their effects on sympathetic nerve activity. Journal of the Science of Food and Agriculture, 98: 4742-4748, 2018.

学会発表 2018年

〇豊⽥梨帆、⼭内恒⽣、光永 徹ウェンジ⼼材の⾊素成分について 2018年度木材学会中部支部大会　10月

〇福岡晃帆、⼭内恒⽣、光永 徹 能登ヒバ材精油⾹気成分がラット交感神経活動に及ぼす効果 2018年度木材学会中部支部大会　10月

〇伊藤弘騎、⼭内恒⽣、光永 徹 サイプレス材精油⾹気成分がラット交感神経活動に及ぼす影響 −guaiol と citronellic acid の量⽐による検討− 2018年度木材学会中部支部大会　10月

〇山口佳穂，晋山典恵，山内恒生，服部浩之，光永徹　Grains of Paradise 種子抽出成分の配糖化とスコポラミン誘導性記憶障害に対する効果　日本生薬学会65回年会　9月

〇Wang Xiaoyu，Kosei Yamauchi，Tohru Mitsunaga　Screening of Indonesian medicinal plants methanol extracts on osteoclastogenesis　日本生薬学会65回年会　9月

〇晋山典恵 ，中島わかほ ，山内恒生 ，光永徹 ，夏目真穂 ，西田義昭 黒ウコン根茎成分ポリメトキシフラボンの神経突起伸長への効果　日本生薬学会65回年会　9月

〇Kaho Yamaguchi, Hiroyuki Hattori, Kosei Yamauchi, Tohru Mitsunaga「Glucosylation of Vaniloid Compounds Contained in Grains of Paradise」The 4th Ineternational Symposium on Temulawak and Potential Plants for Jamu, 2018

〇林友香，山内恒生，光永徹　ヒノキ科樹木精油香気の吸入におけるストレス緩和効果　第68回日本木材学会大会

〇各務裕也，山内恒生，光永徹　 カラマツ (Larix kaempferi) 樹皮抽出成分の構造解析と歯周病原因菌に対する抗菌効果　第68回日本木材学会大会

〇藤枝あかり，山内恒生，光永徹　ルテオリンA環疎水性置換基のメラニン生成抑制活性への寄与　第68回日本木材学会大会

〇晋山典恵，中島わかほ，山内恒生，光永徹　（京扇産業）夏目真穂，西田義昭　黒ウコン根茎由来ポリメトキシフラボンのPC12細胞における樹状突起伸長効果　第68回日本木材学会大会

〇山内恒生，光永徹　Quercetin誘導体のメラノーマ細胞に与える影響　第68回日本木材学会大会

〇夏目　岬，平林佳恵，山内恒生，光永　徹，（ボゴール農科大学）Batubara Irmanida　Zingiber officinale var rubrum根の成分探索およびメラニン生成抑制活性　第68回日本木材学会大会

〇伊藤弘騎，山内恒生，光永徹　ホワイトサイプレス材精油香気のラット交感神経活動の亢進に寄与する成分について　第68回日本木材学会大会

招待講演

Norie Shinyama, Kaho Yamaguchi, Mizuki Takeuchi, Kosei Yamauchi, 〇Tohru Mitsunaga「May the Natural Product Constituents Contribute to Improvement of Alzheimer's Type Dementia？」The 4th Ineternational Symposium on Temulawak and Potential Plants for Jamu, 2018

〇Kosei Yamauchi, Tohru Mitsunaga「Anticancer Activity of Methylquercetins」The 4th Ineternational Symposium on Temulawak and Potential Plants for Jamu, 2018

〇山内 恒生　「薬用植物由来ポリフェノールと生物活性」NPO法人東海地域生物系先端技術研究会 平成30年度第2回セミナー　2018年11月28日

〇山内 恒生　「フラボノイドの美容と健康に与える影響」日本生物工学会中部支部第7回CHUBU懇話会 2018年9月14日

原著論文 2017年

Hattori, H., Yamauchi, K., Onwona-Agyeman, S., Mitsunaga, T., Effect of Grains of Paradise (GP) Extract Intake on Obesity and Sympathetic Nerve Activity. American Journal of Plant Sciences 8: 85-95, 2017.

Muddathir, A.M., Yamauchi, K., Batubara, I., Mohieldin, E.A.M., Mitsunaga, T., Anti-tyrosinase, total phenolic content and antioxidant activity of selected Sudanese medicinal plants. South African Journal of Botany 109: 9-15, 2017.

Yamauchi, K., Mitsunaga, T., Afroze, H.S., Uddin N.M., Structure-activity relationships of methylquercetin on anti-migration and anti-proliferation activity in B16 melanoma cells. Anticancer Research, 37: 1575-1579, 2017.

Yamauchi, K., Afroze, H.S., Mitsunaga, T., Mccormick C.T., Kuehl J.T., Zawieja C.D., Uddin N.M. 3,4',7-O-trimethylquercetin inhibits invasion and migration of ovarian cancer cells. Anticancer Research, 37: 2823-2829, 2017.

Mohieldin, M.E., Muddathir, A.M., Mitsunaga, T., Inhibitory activities of selected Sudanese medicinal plants on Porphyromanas gingivalis and matrix metalloproteinase-9 and hartmannianum (Schweinf) bark. BMC Complementary and Alternative Medicine, 17: 224, 2017.

Mohieldin, E.A.M., Muddathir, A.M., Yamauchi, K., Mitsunaga, T. Anti-caries activity of selected Sudanese medicinal plants with emphasis on Terminalia laxiflora. Brazilian Journal of Pharmacognosy, 27: 611-618, 2017.

光永　徹，　服部浩之　香辛料Grains of Paradise成分の肥満抑制および交感神経活動に与える効果　AROMA RESEARCH 18: 29-34, 2017.

学会発表 2017年

〇Hiroyuki Hattori , Kosei Yamauchi, Tohru Mitsunaga，「Grains of Paradise Extract Affects on Obesity and Sympathetic Nerve Activity in Brown Adipose Tissue」『International symposium on Natural Medicines　2017』, Indonesia, (August 24-25 2017)

〇Norie Shinyama, Kosei Yamauchi, Tohru Mitsunaga，「Mechanism of melanogenesis accelerated activity using quercetin derivatives」『International symposium on Natural Medicines　2017』, Indonesia, (August 24-25 2017)

〇Misaki Natsume, Kae Hirabayashi, Kosei Yamauchi, Tohru Mitsunaga, and Irmanida Batubara，「Melanogenesis Inhibitory Activities of the Methanol Extract of Jahe merah from Indonesia」『International symposium on Natural Medicines　2017』, Indonesia, (August 24-25 2017)

〇Andriyana Setyawati, Kae Hirabayashi, Kosei Yamauchi, Hiroyuki Hattori, Tohru Mitsunaga1, Irmanida Batubara, Rudi Heryanto, Hiroshi Hashimoto, Mitsuyuki Hotta　｢Melanogenesis Inhibitory Acyivity of components from Salam Leaf (Syzygium polyanthum) Extract｣　『第64回日本生薬学会』　千葉　2017年　9月9-10日

〇Siwattra Choodej，Khanitha Pudhom，Kosei Yamauchi, Tohru Mitsunaga　｢Evaluation of sesquiterpene lactones from Saussurea lappa on TNF-α inhibition｣　『第64回日本生薬学会』　千葉　2017年　9月9-10日

〇服部 浩之、山内 恒生、光永 徹　｢香辛料Grains of Paradise成分のラット交感神経活動に与える効果｣　『第64回日本生薬学会』　千葉　2017年　9月9-10日

〇林 友香、山内 恒生、光永 徹、（森林総研）松原 恵理「ヒノキ科木材精油の嗅覚刺激が自律神経活動に及ぼす効果」『2017年度日本木材学会中部支部大会』福井　2017年10月12－13日（優秀発表賞）

〇伊藤 弘騎、山内 恒生、光永 徹「ホワイトサイプレス材香気成分が交感神経に及ぼす効果」『2017年度日本木材学会中部支部大会』福井　2017年10月12－13日

〇須浦 千晶、山内 恒生、光永 徹「沖縄県産タイリン月桃葉精油の香気成分が交感神経に及ぼす影響」『2017年度日本木材学会中部支部大会』福井　2017年10月12－13日

招待講演

〇Tohru Mitsunaga, Tomoka Hayashi「Inhaling woody essential oils influences physiological and psychological factors for animals and humans」『International symposium on Natural Medicines　2017』, Indonesia, (August 24-25 2017)

〇Kosei Yamauchi, Tohru Mitsunaga，「Effects of Quercetin Derivatives in B16 Melanoma Cells」『International symposium on Natural Medicines　2017』, Indonesia, (August 24-25 2017)

原著論文 2016年

Kuspradini, H., Putri, S.A., Sukaton, E., Mitsunaga, T., Bioactivity of essential oils from leaves of Dryobalanops lanceolata, cinnamomum burmannii, Cananga odorata, and Scorodocarpus borneensis. Agriculture and Agricultural Science Procedia 9: 411-418, 2016.

Choodej, S., Teerawatananond, T., Mitsunaga, T., Pudhom, K., Chamigrane sesquiterpenes from a Basidiomycetous Endophytic fungus XG8D associated with Thai Mangrove Xylocarpus granatum. Marine Drugs 14: 132, 2016.

Yamauchi, K., Mitsunaga, T.: Melanogenesis and melanosome transportation modulators from medicinal plants. Letters in Drug Design & Discovery 13: 742-751, 2016.

Yamauchi, K., Mitsunaga, T., Muddathir, A.M., Screening for melanogenesis-controlled agents using Sudanese medicinal plants and identification of active compounds in the methanol extract of Terminalia brownii bark. Journal of wood science 62: 285-293, 2016.

Wang, X., Mitsunaga, T., Yamauchi, K., Antibacterial Activity of Selected Essential oils against Streptococcus sobrinus and Porphyromonas gingivalis. Journal of Pharmaceutical Sciences & Emerging Drugs 4:2, 2016.

原著論文 2015年

Mitsunaga, T., Yamauchi, K., Effect of quercetin derivatives on melanogenesis stimulation of melanoma cells. J. Wood Sci. 61: 351-363, 2015.

Yamauchi, K., Mitsunaga, T., Inagaki, M., Suzuki, T., Quercetin derivatives regulate melanosome transportation via EPI64 inhibition and elongate the cell shape of B16 melanoma cells. Biomedicine & Pharmacotherapy 70: 206-212, 2015.

Yamauchi, K., Mitsunaga, T., Itakura, Y., Batubara, I., Extracellular melanogenesis inhibitory activity and the structure-activity relationships of ugonins from Helminthostachys zeylanica roots. Fitoterapia 104: 69-74, 2015.

Hanum, Z., Sumantri, C., Purwantiningsih, Batubara, I. Taufik, E., Mitsunaga, T., Yamauchi, K., Ogota, Y.:,Effectivity of fermented goat milk added lactobacillus plantarum as melanin inhibitor. Applied Research Journal 1: 338-342, 2015.

Batubara, I., Julita, I., Darusman, K.L., Muddathir, A.M., Mitsunaga, T., Flower bracts of Temulawak (Curcuma Xanthorrhiza) for skin care: Anti-acne and whitening agents. Procedia Chemistry 14: 216-224, 2015.

Batubara, I., Suparto, H.I., Diah, S.S., Matsuoka, R., Mitsunaga, T., Effects of inhaled citronella oil and related compounds on rat body weight and brown adipose tissue sympathetic nerve. Nutrients 7: 1859-1870, 2015.

原著論文 2014年

Batubara I., Kuspradini H., Muddathir A. M., Mitsunaga T., Intsia palembanica wood extracts and its isolated compounds as Propionibacterium acnes lipase inhibitor, J. Wood Sci., 2014

Yamauchi. K., Mitsunaga. T., Batubara, I. Synthesis of quercetin glycosides and their melanogenesis stimulatory activity in B16 melanoma cells. Bioorganic &　Medicinal Chemistry, 22: 937-944, 2014.

Yamauchi. K., Mitsunaga. T., Inagaki. M., Suzuki, T., Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK, Bioorganic & Medicinal Chemistry, 22: 3331-3340, 2014.

Batubara, I., Kuspradini, H., Muddathir, A.M., Mitsunaga, T., Intsia palembanica wood extracts and its isolated compounds as Propionibacterium acnes lipase inhibitor. Journal of wood science 60: 169-174, 2014.

光永　徹：　サイプレス材精油香気成分の肥満抑制食品フレーバーとしての可能性，FOOD & FOOD INGREDIENTS JOURNAL OF JAPAN, Vol.219, No.2, 2014.

Batubara, I., Assaat, L.D., Irawadi, T.T., Mitsunaga, T., Yamauchi. K., Effect of Sniffing of Kencur (Kaemferia galangal) Essential Oils in Rats. Acta Hort. (ISHS) 1023:123-127, 2014.

原著論文 2013年

Batubara I., Mitsunaga T.,: Use of Indonesian Medicinal Plant Products against Acne. Reviews in Agricultural Science 1:11-30, 2013.

Yamauchi, K., Batubara, I. and Mitsunaga, T.,: Novel quercetin glucosides from Helminthostachys zeylanica root and acceleratory activity of melanin biosynthesis, Journal of Natural Medicines, 67:369-374, 2013.　

Imai, K., Yamauchi K., Mitsunaga, T., Extractives of Quercus crispula sapwood infected by the pathogenic fungus Raffaelea quercivora II: isolation and identification of phenolic compounds from infected sapwood., J. Wood Sci., 59, 517-521, 2013.

光永　徹，サイプレス材香気成分の吸入が肥満因子の抑制及び交感神経活動に及ぼす効果，岩手大学「におい」による生物間コミュニケーション研究の推進事業，２０１３年３月２９日，盛岡（招待講演）

Batubara I., Suparto I.H., Sadiah S., Matsuoka R., Mitsunaga T., Effect of Zingiber zerumbet Essential oils and Zerumbone Inhalation on Body Weight of Sprague Dawley Rat, Pakistan Journal of Biological Science, 16(19), 1028-1033, 2013.

Matsufuji Y, Yamamoto K, Yamauchi K, Mitsunaga T, Hayakawa T, Nakagawa T.: Novel physiological roles for glutathione in sequestering acetaldehyde to confer acetaldehyde tolerance in Saccharomyces cerevisiae., Appl Microbiol Biotechnol. 97: 297-303, 2013

Sakaguchi K., Funaoka N., Tani S. Hobo A., Mitsunaga T. and Suzuki T., The pyre gene as ABi-directional Selection Marker in Bifidobacterium Longum 105-A Bioscience of Microbiota, Food and Health, 32(2), 2013.

原著論文 2012年

Darsman, H.S., Rahniniwati, M., Sadiah, S., Batubara, I., Darsman, I. and Mitsunaga, T.: Indonesian Kepel Fruit (Stelechocarpus burahol) as Oral Deodorant, Research Journal of Medicinal Plant, 6, 180-188, 2012.

Batubara, I., Kotsuka, S., Yamauchi, K., Kuspradini, H., Mitsunaga, T. and Darusman, L.K., : TNF- Production Inhibitory Activity, Phenolic, Flavonoid and Tannin Contents of Selected Indonesian Medicinal Plants, Research Journal of Medicinal Plant, 6, 406-415, 2012.

Harlinda Kuspradini, Ritmaleni, Dwi Susanto and Tohru Mitsunaga, : Phytochemical and comparative study of anti microbial activity of Lepisanthes amoena leaves extract, Journal of Biology, Agriculture and Healthcare, Vol.2, No.11, 80-86, 2012.

Darusman LK, Batubara I., Mitsunaga T., M Rahminiwati, E Djauhari, Yamauchi K., Tyrosinase Kinetic Inhibition of Active Compounds from Intsia palembanica. Research Journal of Medicinal Plants. 6(8):615-620, 2012.

Yamauchi, K., Mitsunaga, T., Batubara, I., Melanogenesis acceleratory active compounds from Helminthostachys zeylanica root extract in B16 melanoma cells. Proceedings of The Biocomp 2012 11th Pacific Rim Bio-Based Composites Symposium, 284-291, 2012　

光永　徹：　麻酔下ラットの交感神経活動に及ぼすサイプレス材精油吸入の効果，AROMA RESEARCH,No.51,Vol.13, 209-213, 2012.

光永　徹：　サイプレス（豪州ヒノキ）材精油の吸入が肥満抑制および交感神経活動に及ぼす効果，香料，No.256, 21-29, 2012.

Ryunosuke Matsuoka, Tohru Mitsunaga, Effects of olfactory stimulation with scent of cypress (Callitris glaucophylla), essential oil on brown adipose tissue sympathetic nerve activity of rat, Proceedings of The 2nd International symposium on Temulawak and 40th Meeting of National Working Group on Indonesian Medicinal Plant committee, 2012, 275-279.

Tohru Mitsunaga, Biologically Active Molecules of Plant Secondary Metabolites on Applied Life Science, Proceedings of The 2nd International symposium on Temulawak and 40th Meeting of National Working Group on Indonesian Medicinal Plant committee, 2012（招待講演）

それ以降

タンニン関連研究

• Mitsunaga, T. and Abe, I. : The phenolation of monomeric compound of condensed tannins by Lewis acid catalyst. Mokuzai Gakkaishi 38: 585-592, 1992.
• Mitsunaga, T., Abe, I. and Nogami, T. : The formation of ring-opened compound from (+)-catechin by BF3 catalyst. Mokuzai Gakkaishi 39: 328-332, 1993.
• Mitsunaga, T., Abe, I. and Ohara, S. : The chemical structure and stereochemistry of phenol adduct compound derived from (+)-catechin on the phenolation. Mokuzai Gakkaishi 40: 100-106, 1994.
• Mitsunaga, T., Yoshida, A. and Abe, I. : Analysis on the pyran-ring of the condensed tannins by nucleus exchange reaction. Mokuzai Gakkaishi 41: 193-199, 1995.
• Mitsunaga, T., Kondo, O. and Abe, I. : The phenolation of bark extracts in the presence of borontrifluoride and the reactivity of the products with formaldehyde. Mokuzai Gakkaishi 41: 200-205, 1995.
• Mitsunaga, T. : Structural Modification of Condensed Tannins by the Pyran-Ring Opening. Bul. Mie Univ. Fores. 20: 101-173, 1996.
• Mitsunaga, T., Abe, I., Kontani, M., Ono, H. and Tanaka, T. : Development of the functional utilization of bark polyphenols. Trans. Mat. Res. Soc. Jap. 20: 151-154, 1996.
• Hamada, S., Kontani, M., Hosono, H., Ono, H., Tanaka, T., Ooshima, T., Mitsunaga, T. and Abe, I. : Peroxidase-catalyzed generation of catechin oligomers that inhibit glucosyltransferase from Streptococcus sobrinus. FEMS Micro. Let. 143: 35-40, 1996.
• Mitsunaga, T., Abe, I., Kontani, M., Ono, H. and Tanaka, T. : Inhibitory effects of bark proanthocyanidins on the activities of glucosyltransferases of Streptococcus sobrinus. J. Wood Chem. Tech. 17: 323-340, 1997.
• Mitsunaga, T., Doi, T., Kondo, Y. and Abe, I. : Color development of proanthocyanidins in vanillin-hydrochloric acid reaction. J. Wood Sci. 44: 125-130, 1998.
• Tsutsumi, Y., Shimada, A., Miyano, A., Nishida, T. and Mitsunaga, T. : In vitro screening of angiotensin I-converting enzyme inhibitors from Japanese cedar (Cryptomeria japonica). J. Wood Sci. 44: 463-469, 1998.
• 高木啓二，下村健次，阿部　勲，光永　徹：ジャトバ果皮抽出物のチロシナーゼ活性阻害とメラニン生成抑制作用. 生薬学会誌53: 15-21, 1999.
• 光永　徹，永松和成，西井孝文，大賀祥治：担子菌類の菌糸生長に及ぼす樹皮ポリフェノールの効果. 日本菌学会報40: 91-96, 1999.

薬用植物研究

• 光永　徹：樹皮ポリフェノールの生理活性（総説）. APAST　23: 6-10, 1997.
• 光永　徹，中田一英， 阿部　勲：樹皮ポリフェノールのセルラーゼ阻害作用. 三重大学生物資源学部演習林報告 22: 115-125, 1998.
• Takagi, K. and Mitsunaga, T. : A tyrosinase inhibitor from the wood of Asam (Mangifera quadrifida J.). Natural Medicines 56: 97-103, 2002.
• Aoyama W., Sasaki S., Matsumura S., Mitsunaga T., Hirai H., Tsutsumi Y. and Nishida T. : Sinapyl alcohol-specific peroxidase isoenzyme catalyzes the formation of the dehydrogenative polymer from sinapyl alcohol. J. Wood Sci. 48: 497-504, 2002.
• Takagi, K. and Mitsunaga, T. : Tyrosinase inhibitory activity of proanthocyanidins from woody plants. J. Wood Sci. 49: 461-465, 2003.
• Mihara, R. and Mitsunaga, T. : Investigating glucosyltransferase inhibitory activity of hydolyzable tannins from tropical woody species. 12th ISWPC 277-280, 2003.
• Mitsunaga,T. and Shimozu,Y. : Glucosyltransferase inhibitory activity of the bio-converted catechin by the extracellular enzymes of Pycnoporus coccineus. XXII International Conference on Polyphenols 297-298, 2004.
• Nakai, M., Fukui, Y., Asami, S., Toyoda-Ono, Y., Iwashita, T., Shibata, H., Mitsunaga T., Hashimoto, F. and Kiso, Y. ：Inhibitory Effects of Polyphenols on Pancreatic Lipase in vitro. J. Agric. Food Chem. 53: 4593-4598, 2005.
• Kuspradini, H., Mitsunaga, T., Mihara, R. and Ohashi, H. : Investigating glucosyltransferase inhibitory activities of polyphenols from kapur (Dryobalanops sp) heartwood extracts. J. Nat. Med. 61: 462-467, 2007.
• Batubara, I., Mitsunaga, T. and Ohashi H. : Screening anti-acne potency of Indonesian medicinal plants: antibacterial, lipase inhibition and antioxidant. J. Wood Sci.,55, 230-235 2009.
• Kuspradini, H., Mitsunaga, T., and Ohashi, H.:Anti microbial activity against Streptococcus sobrinus and glucosyltransferase inhibitory activity of taxifolin and some flavanonol rhamnosides from Kempas (Koompassia malaccensis) extracts. J. Wood Sci., 55,308-313, 2009.
• Batubara, I., Mitsunaga, T. and Ohashi H. : Brazilin from Caesalpinia sappan wood as an anti-acne agent, J. Wood Sci., 56, 77-81, 2009.
• Batubara, I., Darusman, L.K., Mitsunaga, T. et al., : Potency of Indonesian Medicinal Plants as Tyrosinase Inhibitor and Antioxidant Agent, Journal of Biological Science, 10, 138-144, 2010.
• Batubara, I., Kuspradini, H., Mitsunaga, T.,: Anti-acne and Tyrosinase Inhibition Properties of Taxifolin and Some Flavanonol Rhamnosides from Kempas (Koompassia malaccensis), Wood Research Journal, Vol. 1, No. 1, 45-49, 2010.
• Kuspladini H., Batubara I., Mitsunaga T.,: Antimicrobial and GTase inhibitory activity of crude methanol extracts of olants from Java and Kalimantan, Journal of Tropical Wood Science and Technology, Vol.8, No.1, 39-46, 2010.
• Yamauchi, K., Mitsunaga, T. and Batubara, I. : Isolation, Identification and Tyrosinase Inhibitory Activities of the Extractives from Allamanda cathartica, Natural Resources, 2, 167-172, 2011.
• Batubara, I., Darusman, L.K., Mitsunaga, T., Aoki, H., Rahminiwati, M., Djauhari, E., Yamauchi, K.: Flavonoid from Intsia palembanica as Skin Whitening Agent., Journal of Biological Science 11(8), 475-480, 2011.

植物・樹木生理機能成分関連

• 笠井美和, 光永　徹, 伊藤進一郎, 鎌田直人: カシノナガキクイムシに被害を受けたミズナラの抽出成分に関する研究. 中部森林研究 51: 195-198, 2003.
• 小穴久仁, 垣内信子, 江崎功二郎, 伊藤進一郎, 御影雅幸, 鎌田直人, 光永　徹: カシノナガキクイムシの穿孔による壊死変色部と健全材との成分の比較. 中部森林研究 51: 189-190 , 2003.
• Kasai, M., Mitsunaga, T., Ito, S. and Kamata, S. : Study on extractives of Quercus crispula wood damaged by Platypus quercivorus attack. IUFROWorkshop 138, 2003.
• Oana, H., Kakiuchi, N., Mikage, M., Kamata, N., Esaki, K., Mitsunaga, T. and Ito, S. : Reaction of the Ambrosia Beetle Platypus quercivorus to Gallic Acid in Oak Sapwood. IUFROWorkshop 149, 2003.
• Takemoto, H., Mitsunaga, T., Ito, S., Kamata, N. and Kobayashi, M. : Volatile compounds related to attractant of Platypus quercivorous from Quercus crispula. IUFROWorkshop 150-153, 2003.
• Takemoto, H., Kasai, M., Mitsunaga, T. and Itho, S. : Extracts from Quercus crispula sapwood infected by the pathogenic fungi Raffaelea quercivorous causing the mass mortality of oak trees in Japan. XXIIInternational Conference on Polyphenols 809-810, 2004.
• Mihara,R., Barry,K.M., Mohammed,C.L. and Mitsunaga,T. : Comparison of antifungal of Acacia mangium and A. auriculiformis heartwood extracts. XXIIInternational Conference on Polyphenols 799-800, 2004.
• Mihara, R., Mitsunaga, T., Fukui, Y., Nakai, M., Yamaji, N. and Shibata, H. : A novel acylated quercetin tetraglycoside from oolong tea (Camelia sinensis) extracts. Tetrahedron Letters 45: 5077-5080, 2004.
• Eyles, A., Davies, N.W., Mitsunaga, T., Mihara, R. and Mohammed, C. : Role of Eucalyptus globuleswound wood extractives： evidence of superoxide dismutase-like activity. Forest Pathology 34: 225-232, 2004.
• Mihara, R., Barry, K. M., Mohammed, C. L. and Mitsunaga，T. : Comparison of antifungal and antioxidant activities of Acacia mangium and A. auriculiformisheartwood Extracts. J. Chem. Ecology 31: 789 - 804, 2005.
• Barry, K. M., Mihara, R., Davies, N. W., Mitsunaga T. and Mohammed C. L. : Polyphenols in Acacia mangium and A. auriculiformis heartwood with reference to heartrot susceptibility. J.Wood Sci. 51: 615-621, 2005.
• Kamata, N., Esaki, K., Mori, K., Takemoto, H., Mitsunaga, T. and Honda, H. : Field trap test for bioassay of synthetic (1S,4R)-4-isopropyl-1-methyl-2-cyclohexen-1-ol as an aggregation pheromone of Platypus quercivorus(Coleoptera: Platipodidae). J. Forest Res. 13: 122-126, 2008.
• Imai, K., Mitsunaga, T., Takemoto, H., Yamada, T., Ito, S. and Ohashi H. : Extractives of Quercus crispula sapwood infected by the pathogenic fungi Raffaelea quercivora (I)-Comparison of sapwood extractives non-infected and infected-. J. Wood Sci., 55, 126-132, 2009.

香り・テルペン研究

• Watanabe, Y., Murakumo, I. and Mistunaga, T. : Investigating biologically active compounds from Australian white cypress heartwood (Callitris glaucophylla). 12th ISWPC269-272, 2003
• Watanabe, Y., Mitsunaga, T. and Yoshimura, T. ：.Investigating antitermitic compounds from Australian white cypress heartwood (Callitris glaucophylla Thompson et Johnson) against Coptotermes formosanusShiraki. J. Essential Oil Res. 23: 234-241, 2004.
• Watanabe, Y., Mihara, R., Mitsunaga, T. and Yoshimura T. ：Termite repellent sesquiterpenoids from Callitris glaucophylla heartwood. J.Wood Sci. 51: 514-519, 2005.
• 光永　徹，渡邊泰高：　サイプレスパイン（豪州ヒノキ）材の抗シロアリ活性に寄与する抽出成分について（総説）. しろあり149: 1-10 2008.
• 光永　徹，田丸貴絵：　サイプレス（豪州ヒノキ）材精油による脂肪蓄積抑制効果. AROMA RESEARCH34: 10-14, 2008.
• 光永　徹: サイプレス材精油によるマウス・ラットの脂肪蓄積抑制効果（総説）. グリーンスピリッツ，Vol.4 No.3, 2008.
• 光永　徹：　抗肥満作用のあるテルペン類，ファインケミカルス，Vol.40, No.4, 34-38, 2011.

その他の研究

• 近藤隆一郎，光永　徹， 今村博之: 木材の色に関する研究（第２報）ムラサキタガヤサン(Milettia sp.) の変色過程と環境要因. 木材学会誌 32:462-466, 1986.
• Mitsunaga, T., Kondo, R. and Imamura, H.: The Chemistry of Color of Wood III. The isoflavanoids of heartwood of murasakitagayasan (Milletia sp.). Mokuzai Gakkaishi 33: 234-238, 1987.
• 光永　徹，近藤隆一郎，今村博之： 木材の色に関する研究（第４報）ムラサキタガヤサン(Milletia　sp.)心材の濃紫色化に寄与するフェノール成分について. 木材学会誌33: 239-245, 1987.
• 光永　徹：縮合型タンニンの接着剤への応用に関する基礎研究（総説）. APAST34: 22-26, 2000.
• Mitsunaga, T.,Conner, A. and Hill, C. : Reaction of formaldehyde with phenols: A computational chemistry study. Wood Adhesives 2000 147-153, 2001.
• Mitsunaga, T.,Conner, A. and Hill, C. : Predicting the hydroxymethylation rate of phenols with formaldehyde by molecular orbital calculation. J. Wood Sci. 48: 153-158, 2002.
• Mitsunaga, T., Conner, A. and Hill, C. : Predicting the reactivity of phenolic compounds with formaldehyde II.Continuation of ab initio study. J. Appl. Polym. Sci. 86: 135-140, 2002.
• Mitsunaga, T., Saitoh, Y., Abiko S. and Mizuno, D. : Deodorant activity of coniferous barks and proanthocyanidins on ammonia and methyl mercaptan. 12th ISWPC273-276, 2003.
• 斉藤靖英，渡辺泰高，光永　徹　等：　竹炭添加食品の摂取によるヒト排便臭抑制およびマウス血清脂質低減効果. 木質炭化学会誌 １: 84-89, 2005.

著書・特許

著書

• Mitsunaga, T. : Anti-caries activity of bark proanthocyanidins. In: Plant Polyphenols 2 Chemistry, Biology, Medicine and Ecology. Gross, G. G., Hemingway, R. W. and Yoshida, T. eds. Plenum Press, New York and London, ISBN0-306-46218-4, pp. 555-574, 1999 (共著).
• 光永　徹：樹木の顔　樹木抽出成分の効用と利用. 海青社, ISBN4-906165-85-0, pp. 213-220, pp. 291-293, 2002　（共著）.
• 光永　徹：木質の形成　バイオマス科学への招待. 海青社, ISBN4-86099-202-4, pp. 273-277, pp. 296-300, pp. 307-310, 2003 （共著）.　
• 光永　徹：木のびっくり話, 講談社, ISBN4-06-212962-0, pp. 60-61, 2005 （共著）.
• 光永　徹：木質の化学, 文永堂出版社, ISBN978-4-8300-4118-1,2010 （共著）.
• 光永　徹：木質の形成（第2版）　バイオマス科学への招待. 海青社, ISBN4-86099-202-4, pp. 273-277, pp. 296-300, pp. 307-310, 2011 （共著）.　

特許

• 光永　徹，島田裕治：接着剤樹脂組成物, 特許番号：第1893915号, 1994. 3.
• 光永　徹，登賢太郎：新規ヒドロキシル基含有塩素化ポリオレフィン及びその製法と組成物，特許番号：第1938844号, 1994. 9.
• 高岡睦男，光永　徹：ヒドロキシル基含有変性塩素化ポリオレフィン組成物とその製法，特許番号：第1896519号, 1994. 4.
• 阿部　勲，光永　徹，高木啓二，下村健次：美白化粧品，特許番号：第3650245号, 2005. 2.
• 近藤　敏，光永　徹： 抗炎症剤，特許番号；第4315255 号，2009.6.