国立大学法人東海国立大学機構 岐阜大学 応用生物科学部

動物生産管理学研究室

研究業績

原著論文

  • Otsuka. T, Le. HT, Thein ZL, Ihara. H, Sato. F, Nakao. T, Kohsaka. A Deficiency of the circadian clock gene Rev-erbα induces mood disorder-like behaviours and dysregulation of the serotonergic system in mice. Physiology and behavior 256 113960 (2022)

  • Otsuka. T, Le. HT, Kohsaka. A, Sato. F, Ihara. H, Nakao. T, Maeda. M Adverse Effects of Circadian Disorganization on Mood and Molecular Rhythms in the Prefrontal Cortex of Mice. Neuroscience 432 44-54 (2020)
  • Sato. F, Otsuka. T, Kohsaka. A, Le. HT, Bhawal. UK, Muragaki. Y Smad3 suppresses epithelial cell migration and proliferation via the clock gene Dec1, which negatively regulates the expression of clock genes Dec2 and Per1. The American Journal of Pathology 189 (4) 773-783 (2019)
  • Nakao. T,Kohsaka. A, Otsuka. T, Thein. ZL, Le. HT, Waki. H, Gouraud. SS, Ihara. H, Nakanishi. M, Sato. F, Muragaki. Y,Maeda. M Impact of heart-specific disruption of the circadian clock on systemic glucose metabolism in mice. Chronobiology International 35(4): 499-510 (2018)
  • Nagasawa. M, Otsuka. T, Togo. Y, Yamanaga. M, Yoshida. J, Uotsu. N, Teramoto. S, Yasuo. S, Furuse. M Single and chronic L-serine treatments exert antidepressant-like effects in rats possibly by different means. Amino acids 49(9): 1561-70 (2017)
  • Minaminaka. K, Nagasawa. M, Ikeda. H, Otsuka. T, Kawase. T, Tagashira. H, Tsubata. M, Furuse. M Flavangenol attenuates stress responses in mice exposed to unpredictable chronic mild stress. Current Topics in Phytochemistry 13: 43-51 (2016)
  • Otsuka. T, Goda. R, Iwamoto. A, Kawai. M, Shibata. S, Oka. Y, Mizunoya. W, Furuse. M, Yasuo. S Dietary protein ingested before and during short photoperiods makes an impact on affect-related behaviours and plasma composition of amino acids in mice. British Journal of Nutrition 114(10): 1734-43 (2015)
  • Kawai. M, Goda. R, Otsuka. T, Iwamoto. A, Uotsu. N, Furuse. M, Yasuo. S Antidepressant-effect of bright light is potentiated by L-serine administration in a mouse model of seasonal affective disorder. Brain Research Bulletin 118: 25-33 (2015)
  • Nagasawa. M, Otsuka. T, Yasuo. S, Furuse. M Chronic imipramine treatment differentially alters the brain and plasma amino acid metabolism in Wistar and Wistar Kyoto rats. European journal of Pharmacology 762: 127-135 (2015)
  • Goda. R, Otsuka. T, Iwamoto. A, Kawai. M, Shibata. S, M, Furuse. M, Yasuo. S Serotonin levels in the dorsal raphe nuclei of both chipmunks and mice are enhanced by long photoperiod, but brain dopamine level response to photoperiod is species-specific. Neuroscience leters 593: 95-100 (2015)
  • Nagy. AD, Iwamoto. A, Kawai. M, Goda. R, Matsuo. H, Otsuka. T, Nagasawa. M, Furuse. M, Yasuo. S Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder. Chronobiology International 32(4): 447-57 (2014)
  • Matsuo. H, Iwamoto. A, Otsuka. T, Hishida. Y, Akiduki. S, Aoki. M, Furuse. M, Yasuo. S Effects of time of L-ornithine administration on the diurnal rhythms of plasma glowth hormone, melatonin, and corticosterone levels in mice. Chronobiology International 32(2): 225-34 (2014)
  • Erwan. E, Chowdhury. VS, Nagasawa. M, Goda. R, Otsuka. T, Yasuo. S, Furuse. M Central injection of L- and D- aspartate attenuates isolation-induced stress behavior in chicks possibly through different mechanisms. European Journal of Pharmacology 736: 138-42 (2014)
  • Nagasawa. M,Otsuka. T, Ogino. Y, Yoshida. J, Tomonaga. S, Yasuo. S, Furuse. M Orally administrated whole egg demonstrates antidepressant-like effects in the forced swimming test in rats. Acta Neuropsychiatrica 26(4): 209-17 (2014)
  • Erwan. E, Chowdhury. VS, Nagasawa. M, Goda. R, Otsuka. T, Yasuo. S, Furuse. M Oral administration of D-aspartate, but not L-aspartate, depresses rectal temperature and alters plasma metabolites in chicks. Life Sciences 109(1): 65-71 (2014)
  • Otsuka. T, Kawai. M, Togo. Y, Goda. R, Kawase. T, Matsuo. H, Iwamoto. A, Nagasawa. M, Furuse. M, Yasuo. S Photoperiodic responses of depression-like behavior, the brain serotonergic system, and peripheral metabolism in laboratory mice. Psychoneuroendocrinology 40: 37-47 (2014)
  • Nagasawa. M, Ogino. Y, Kurata. K,Otsuka. T, Yoshida. J, Tomonaga. S, Furuse. M Hypothesis with abnormal amino acid metabolism in depression and stress vulnerability in Wistar Kyoto rats. Amino Acids 43(5): 2101-11 (2012)
  • Togo. Y, Otsuka. T, Goto. M, Furuse. M, Yasuo. S Photoperiod regulates dietary preferences and energy metabolism in young developing Fischer 344 rats, but not in same age Wistar rats. American Journal of Physiology Endocrinology and Metabolism 15;303(6): E777-86 (2012)
  • Otsuka. T, Goto. M, Kawai. M, Togo. Y, Sato. K, Katoh. K, Furuse. M, Yasuo. S Photoperiod regulates corticosterone rhythms by altered adrenal sensitivity via melatonin-independent mechanisms in Fischer 344 rats and C57BL/6J mice. PLoS ONE 7(6): e39090 (2012)